Brand  (β version)

PDB ID: 6O4X

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Ligands
Code Name Style Show Link
AA 9-aminoacridine PoSSuM
GOL Glycerol PoSSuM
NO3 Nitrate ion PoSSuM
Non-standard Residues
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Glycosylation
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Modification
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Structure summary

Code : 6O4X   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Binary complex of native hAChE with 9-aminoacridine
Release Data : 2019-06-19
Compound :
mol_id molecule chains synonym
1 Acetylcholinesterase A,B AChE
ec: 3.1.1.7
fragment: residues 32-578
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: ACHE
expression_system_common: Human
expression_system_cell_line: HEK293
Authors : Gerlits, O., Kovalevsky, A., Radic, Z.
Keywords : HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.3 Å )
Citation :

A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies.

Gerlits, O.,Ho, K.Y.,Cheng, X.  et al.
(2019)  Chem.Biol.Interact.  309 : 108698 - 108698

PubMed: 31176713
DOI: 10.1016/j.cbi.2019.06.011

Reaction

Chain : A, B
UniProt : P22303 (ACES_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
acetylcholine + H2O = choline + acetate + H(+) 3.1.1.7 PubMed:1517212
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