Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
CL Chloride ion
0V5 (2r)-2-(phosphonooxy)propanoic acid
CIT Citric acid
EDO 1,2-ethanediol
Code : 6NKJ
Header : TRANSFERASE
Title : 1.3 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Streptococcus pneumoniae in Complex with (2R)-2-(phosphonooxy)propanoic acid.
Release Data : 2019-01-16
Compound :
mol_id molecule chains synonym
1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 A,B Enoylpyruvate transferase 1,UDP-N-acetylglucosamine enolpyruvyl transferase 1,EPT 1
ec: 2.5.1.7
Source :
mol_id organism_scientific expression_system
1 Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)  (taxid:170187) Escherichia coli BL21(DE3)  (taxid:469008)
strain: ATCC BAA-334 / TIGR4
gene: murA1, murA, SP_1966
expression_system_strain: BL21 (DE3) MAGIC
expression_system_vector_type: plasmid
expression_system_plasmid: pMCSG53
Authors : Minasov, G., Shuvalova, L., Dubrovska, I., Kiryukhina, O., Grimshaw, S., Kwon, K., Anderson, W.F., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, (2R)-2-(phosphonooxy)propanoic acid, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.30 Å )
Citation :

1.3 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Streptococcus pneumoniae in Complex with (2R)-2-(phosphonooxy)propanoic acid.

Minasov, G.,Shuvalova, L.,Dubrovska, I.  et al.
To Be Published 

Chain : A, B
UniProt : Q97NQ4 (MURA1_STRPN)
Reaction : Phosphoenolpyruvate + UDP-N-acetyl-alpha-D- glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha- D-glucosamine.