PDB ID: 6NF1
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Code | Name | Style | Show | Link | |
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9JY | (2s)-3-[(3s)-1-(ethylsulfonyl)piperidin-3-yl]-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}propan-1-ol | PoSSuM | |||
MES | 2-(N-morpholino)-ethanesulfonic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 6NF1
Structure summary
Code : | 6NF1 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | METAL BINDING PROTEIN/INHIBITOR | ||||||||||||
Title : | Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity | ||||||||||||
Release Data : | 2019-12-25 | ||||||||||||
Compound : |
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Source : |
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Authors : | Knapp, M.S., Elling, R.A., Ornelas, E. | ||||||||||||
Keywords : | GEF, Rac, Vav1, inhibitor, METAL BINDING PROTEIN-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.6000 Å ) | ||||||||||||
Citation : |
Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity
Gerspacher, M.,Skaanderup, P.R.
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Reaction
Chain : | A |
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UniProt : | P15498 (VAV_HUMAN) |
Reaction : | - |