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Ligands
Code Name Style Show Link
JYP Adenophostin a
Non-standard Residues
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Glycosylation
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Code : 6MU1   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Structure of full-length IP3R1 channel bound with Adenophostin A
Release Data : 2018-12-05
Compound :
mol_id molecule chains synonym
1 Inositol 1,4,5-trisphosphate receptor type 1 A,C,B,D IP3 receptor isoform 1,InsP3R1,Type 1 inositol 1,4,5-trisphosphate receptor,Type 1 InsP3 receptor
Source :
mol_id organism_scientific organism_common
1 Rattus norvegicus  (taxid:10116) Rat
Authors : Serysheva, I.I., Fan, G., Baker, M.R., Wang, Z., Seryshev, A., Ludtke, S.J., Baker, M.L.
Keywords : inositol 1, 4, 5-trisphosphate receptor, calcium release channel, neuronal type 1, adenophostin A, MEMBRANE PROTEIN, IP3R-channel activator
Exp. method : ELECTRON MICROSCOPY ( 4.1 Å )
Citation :

Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.

Fan, G.,Baker, M.R.,Wang, Z.  et al.
(2018)  Cell Res.  28 : 1158 - 1170

PubMed: 30470765
DOI: 10.1038/s41422-018-0108-5

Chain : A, C, B, D
UniProt : P29994 (ITPR1_RAT)
Reaction : -