Het-PDB Navi2 (PDB: 6MSO)

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Color scheme of protein:

Ligands
Code	Name	Link
SF4	Iron/sulfur cluster	PoSSuM
GOL	Glycerol	PoSSuM
1PE	Pentaethylene glycol	PoSSuM
JYD	(2s)-2-sulfanylbutanedioic acid	PoSSuM

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Download interaction data: 6MSO

Code :

6MSO PDBj RCSB PDB PDBe

Header :

LYASE/LYASE inhibitor

Title :

Crystal structure of mitochondrial fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate

Release Data :

2019-01-30

Compound :

mol_id	molecule	chains
1	fumarate hydratase	A,B,C,D
	ec: 4.2.1.2

Source :

mol_id	organism_scientific	expression_system
1	Leishmania major (taxid:5664)	Escherichia coli (taxid:562)
	gene: LMJF_24_0320

Authors :

Feliciano, P.R., Drennan, C.L., Nonato, M.C.

Keywords :

inhibitor, mitochondrial, fumarate hydratase, LYASE, LYASE-LYASE inhibitor complex

Exp. method :

X-RAY DIFFRACTION ( 2.053 Å )

Citation :

Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.

Feliciano, P.R.,Drennan, C.L.,Nonato, M.C.
(2019) ACS Chem. Biol. 14 : 266 - 275

Chain :

A, B, C, D

UniProt :

Q4QAU9 (FUM1_LEIMA)

PDB ID: 6MSO