Brand  (β version)

PDB ID: 6MPQ

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
JXG (2s,5r)-1-formyl-3-methyl-5-[(sulfooxy)amino]-1,2,5,6-tetrahydropyridine-2-carboxamide PoSSuM
Non-standard Residues
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KCX Lysine nz-carboxylic acid
Glycosylation
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Structure summary

Code : 6MPQ   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE Inhibitor
Title : 1.95 Ang crystal structure of OXA-24/40 beta-lactamase in complex the inhibitor ETX2514
Release Data : 2019-02-27
Compound :
mol_id molecule chains synonym
1 Beta-lactamase A Beta-lactamase OXA-33,Betalactamase OXA24,Carbapenem-hydrolyzing beta-lactamase OXA-40,Carbapenem-hydrolyzing oxacillinase,Carbapenem-hydrolyzing oxacillinase OXA-40,Carbapenemase OXA-24,Class D beta-lactamase OXA-40,OXA24 B-lactamase,Oxa40
Source :
mol_id organism_scientific expression_system
1 Acinetobacter baumannii  (taxid:470) Escherichia coli  (taxid:562)
gene: blaOXA-33, bla-OXA-40, blaOXA-24, blaOXA-40, oxa-24, oxa40
Authors : van den Akker, F., Kumar, V.
Keywords : beta-lactamase, inhibitor, complex, HYDROLASE, HYDROLASE-HYDROLASE Inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 1.9500 Å )
Citation :

Targeting Multidrug-ResistantAcinetobacterspp.: Sulbactam and the Diazabicyclooctenone beta-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent.

Barnes, M.D.,Kumar, V.,Bethel, C.R.  et al.
(2019)  MBio  10

PubMed: 30862744
DOI: 10.1128/mBio.00159-19

Reaction

Chain : A
UniProt : Q8RLA6 (Q8RLA6_ACIBA)
Reaction : -