Het-PDB Navi2 (PDB: 6MII)

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Ligands
Code	Name	Link
08T	[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium	PoSSuM
ADP	Adenosine-5'-diphosphate	PoSSuM
MG	Magnesium ion	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 6MII

Code :

6MII PDBj RCSB PDB PDBe

Header :

HYDROLASE/DNA

Title :

Crystal structure of minichromosome maintenance protein MCM/DNA complex

Release Data :

2019-07-24

Compound :

mol_id	molecule	chains
1	Minichromosome maintenance protein MCM	A,B,C,D,E,F
	ec: 3.6.4.12 mutation: UNP residues 2-265, GGSGGS linker, UNP residues 275-612

mol_id	molecule	chains
2	DNA (5'-D(PTPTPTPTPTPTPTPTPTPT)-3')	X

Source :

mol_id	organism_scientific	expression_system
1	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (taxid:273057)	Escherichia coli BL21(DE3) (taxid:469008)
	strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2 gene: MCM, SSO0774 expression_system_strain: BL21(DE3)-RIPL expression_system_vector_type: plasmid expression_system_plasmid: pEE078.1

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Enemark, E.J., Meagher, M., Epling, L.B.

Keywords :

MCM, DNA, helicase, AAA+, HYDROLASE-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 3.15 Å )

Citation :

DNA translocation mechanism of the MCM complex and implications for replication initiation.

Meagher, M.,Epling, L.B.,Enemark, E.J.
(2019) Nat Commun 10 : 3117 - 3117

Chain :

A, B, C, D, E, F

UniProt :

Q9UXG1 (MCM_SACS2)

PDB ID: 6MII