Brand  (β version)

PDB ID: 6MGR

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
JQS 5-[(z)-(aminomethylidene)amino]-1-(5-O-phosphono-beta-D-ribofuranosyl)-1h-imidazole-4-carboxylic acid PoSSuM
K Potassium ion PoSSuM
MPD (4s)-2-methyl-2,4-pentanediol PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 6MGR   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Title : Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor Oxanosine monophosphate
Release Data : 2018-10-24
Compound :
mol_id molecule chains synonym
1 Inosine monophosphate dehydrogenase A,B,C,D IMP dehydrogenase
ec: 1.1.1.205
Source :
mol_id organism_scientific expression_system
1 Campylobacter jejuni  (taxid:197) Escherichia coli  (taxid:469008)
gene: C9J79_08320
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pMCSG7
Authors : Kim, Y., Maltseva, N., Yu, R., Hedstrom, L., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : IMPDH, TIM barrel, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.97 Å )
Citation :

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor Oxanosine Monophosphate

Kim, Y.,Maltseva, N.,Yu, R.  et al.
To Be Published 

Reaction

Chain : A, B, C, D
UniProt : A0A2R4D3F6 (A0A2R4D3F6_CAMJU)
Reaction: EC: Evidence:
Physiological Direction:
H2O + IMP + NAD(+) = H(+) + NADH + XMP 1.1.1.205 ARBA:ARBA00024264, HAMAP-Rule:MF_01964, RuleBase:RU003928
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