PDB ID: 6ME9
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Structure summary
Code : | 6ME9 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | MEMBRANE PROTEIN | ||||||||||||
Title : | XFEL crystal structure of human melatonin receptor MT2 in complex with ramelteon | ||||||||||||
Release Data : | 2019-04-24 | ||||||||||||
Compound : |
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Source : |
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Authors : | Johansson, L.C., Stauch, B., McCorvy, J., Han, G.W., Patel, N., Batyuk, A., Gati, C., Li, C., Grandner, J., Hao, S., Olsen, R.H.J., Tribo, A.R., Zaare, S., Zhu, L., Zatsepin, N.A., Weierstall, U., Liu, W., Roth, B.L., Katritch, V., Cherezov, V. | ||||||||||||
Keywords : | GPCR, melatonin receptor type 1B (MT2), membrane protein, ramelteon, XFEL, LCP, BRIL, Rubredoxin, circadian rhythm, jetlag, type 2 diabetes | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.30 Å ) | ||||||||||||
Citation : |
XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Johansson, L.C.,Stauch, B.,McCorvy, J.D.
et al.
PubMed: 31019305 |
Reaction
Chain : | A, B |
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UniProt : | P0ABE7 (C562_ECOLX) |
Reaction : | - |
Chain : | A, B |
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UniProt : | P49286 (MTR1B_HUMAN) |
Reaction : | - |
Chain : | A, B |
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UniProt : | P00268 (RUBR_CLOPA) |
Reaction : | - |