Het-PDB Navi2 (PDB: 6M9H)

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Ligands
Code	Name	Link
DMS	Dimethyl sulfoxide	PoSSuM
GOL	Glycerol	PoSSuM
J9D	4-({4-amino-6-[4-(2-hydroxyethyl)-1h-imidazol-1-yl]pyrimidin-2-yl}amino)benzonitrile	PoSSuM

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Download interaction data: 6M9H

Code :

6M9H PDBj RCSB PDB PDBe

Header :

TRANSFERASE/TRANSFERASE INHIBITOR

Title :

JAK2 JH2 in complex with diaminopyrimidine JAK040

Release Data :

2018-09-05

Compound :

mol_id	molecule	chains	synonym
1	Tyrosine-protein kinase JAK2	A	Janus kinase 2,JAK-2
	ec: 2.7.10.2 mutation: W659A, W777A, F794H

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Spodoptera frugiperda (taxid:7108)
	gene: JAK2

Authors :

Puleo, D.E., Schlessinger, J., Jorgensen, W.L.

Keywords :

TRANSFERASE/TRANSFERASE INHIBITOR, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 1.790 Å )

Citation :

JAK2 JH2 Binders

Puleo, D.E.,Schlessinger, J.
To Be Published

PDB ID: 6M9H