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Ligands
Code Name Style Show Link
ZN Zinc ion
Non-standard Residues
Code Name Show
C38 5-iodo-2'-deoxy-cytidine-5'-monophosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 6K3K   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/DNA
Title : Solution structure of APOBEC3G-CD2 with ssDNA, Product B
Release Data : 2019-06-12
Compound :
mol_id molecule chains synonym
1 DNA dC->dU-editing enzyme APOBEC-3G A APOBEC-related cytidine deaminase,ARCD,APOBEC-related protein 9,ARP-9,CEM-15,CEM15,Deoxycytidine deaminase,A3G
ec: 3.5.4.-
mol_id molecule chains
2 DNA/RNA (5'-D(*AP*TP*TP*CP*UP*(ICY)P*AP*AP*TP*T)-3') B
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: APOBEC3G
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Cao, C., Yan, X., Lan, W., Wang, C.
Keywords : APOBEC3G, DNA cytidine deaminase complex with DNA, HYDROLASE-DNA complex
Exp. method : SOLUTION NMR
Citation :

Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.

Yan, X.,Lan, W.,Wang, C.  et al.
(2019)  Chem Asian J  14 : 2235 - 2241

PubMed: 31116511
DOI: 10.1002/asia.201900480

Chain : A
UniProt : Q9HC16 (ABC3G_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxycytidine in single-stranded DNA + H(+) + H2O = a 2'- deoxyuridine in single-stranded DNA + NH4(+) 3.5.4.38 PubMed:12808465, PubMed:18288108, PubMed:18849968, PubMed:19153609
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