Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
9AU 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one
ACT Acetate ion
FMN Flavin mononucleotide
ORO Orotic acid
SO4 Sulfate ion
Code : 6IDJ
Header : MEMBRANE PROTEIN
Title : Crystal structure of human DHODH in complex with ferulenol
Release Data : 2019-09-11
Compound :
mol_id molecule chains synonym
1 Dihydroorotate dehydrogenase (quinone), mitochondrial A DHOdehase,Dihydroorotate oxidase
ec: 1.3.5.2
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: DHODH
Authors : Shiba, T., Inaoka, D.K., Sato, D., Hartuti, E.D., Amalia, E., Nagahama, M., Yoshioka, Y., Matsubayashi, M., Balogun, E.O., Tsuji, N., Kita, K., Harada, S.
Keywords : Coccidium, mitochondria, electron transport chain, dihydroorotate dehydrogenase, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Structural and functional features of Eimeria tenella dihydroorotate dehydrogenase, a potential drug target

Shiba, T.,Inaoka, D.K.,Sato, D.  et al.
To Be Published 

Chain : A
UniProt : Q02127 (PYRD_HUMAN)
Reaction : (S)-dihydroorotate + a quinone = orotate + a quinol.