Brand  (β version)

PDB ID: 6I2K

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Ligands
Code Name Style Show Link
906 1-(2-aminopyridin-4-yl)-3-[(3s)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 6I2K   PDBj   RCSB PDB   PDBe
Header : VIRUS
Title : Structure of EV71 complexed with its receptor SCARB2
Release Data : 2018-11-28
Compound :
mol_id molecule chains
1 Polyprotein A
mol_id molecule chains
2 Polyprotein B
mol_id molecule chains
3 Polyprotein C
mol_id molecule chains
4 Polyprotein D
mol_id molecule chains synonym
5 Lysosome membrane protein 2 E 85 kDa lysosomal membrane sialoglycoprotein,LGP85,CD36 antigen-like 2,Lysosome membrane protein II,LIMP II,Scavenger receptor class B member 2
Source :
mol_id organism_scientific
1 Enterovirus A71  (taxid:39054)
mol_id organism_scientific
2 Enterovirus A71  (taxid:39054)
mol_id organism_scientific
3 Enterovirus A71  (taxid:39054)
mol_id organism_scientific
4 Enterovirus A71  (taxid:39054)
mol_id organism_scientific organism_common expression_system
5 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: SCARB2, CD36L2, LIMP2, LIMPII
expression_system_cell_line: HEK293T
Authors : Zhou, D., Zhao, Y., Kotecha, A., Fry, E.E., Kelly, J., Wang, X., Rao, Z., Rowlands, D.J., Ren, J., Stuart, D.I.
Keywords : Enterovirus 71, SCARB2, Hand-foot-mouth disease, EV71 receptor, VIRUS
Exp. method : ELECTRON MICROSCOPY ( 3.4 Å )
Citation :

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.

Zhou, D.,Zhao, Y.,Kotecha, A.  et al.
(2019)  Nat Microbiol  4 : 414 - 419

PubMed: 30531980
DOI: 10.1038/s41564-018-0319-z

Reaction

Chain : B
UniProt : D4QGA2 (D4QGA2_HE71)
Reaction : -
Chain : C
UniProt : D4QGA3 (D4QGA3_HE71)
Reaction : -
Chain : D
UniProt : Q6YLE3 (Q6YLE3_HE71)
Reaction : -
Chain : E
UniProt : Q14108 (SCRB2_HUMAN)
Reaction : -