PDB ID: 6HME
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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EDO | 1,2-ethanediol | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
FXB | 5-propan-2-yl-4-prop-2-enoxy-7,8-dihydro-6~{H}-indeno[1,2-B]indole-9,10-dione | PoSSuM |
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Download interaction data: 6HME
Structure summary
Code : | 6HME PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | LOW-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA; CSNK2A1 gene product) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR THN27 | ||||||||||||
Release Data : | 2019-03-27 | ||||||||||||
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Authors : | Niefind, K., Lindenblatt, D., Jose, J., Le Borgne, M. | ||||||||||||
Keywords : | protein kinase CK2, casein kinase 2, catalytic subunit CK2alpha, CSNK2A1, indenoindole-type inhibitor, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.850 Å ) | ||||||||||||
Citation : |
Diacritic Binding of an Indenoindole Inhibitor by CK2 alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2 alpha ' Structures.
Lindenblatt, D.,Nickelsen, A.,Applegate, V.M.
et al.
PubMed: 31559376 Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2alpha and Its Paralog CK2alpha'
Hochscherf, J.,Lindenblatt, D.,Witulski, B.
et al.
PubMed: 29236079 Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.
Ermakova, I.,Boldyreff, B.,Issinger, O.G.
et al.
PubMed: 12860116 |
Reaction
Chain : | A, B | ||||||||||||||
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UniProt : | P68400 (CSK21_HUMAN) | ||||||||||||||
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