PDB ID: 6GXU
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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ZN | Zinc ion | PoSSuM | |||
K | Potassium ion | PoSSuM | |||
FG8 | (~{E})-3-[2-(4-chlorophenyl)sulfanylphenyl]-~{N}-oxidanyl-prop-2-enamide | PoSSuM | |||
DMF | Dimethylformamide | PoSSuM | |||
GOL | Glycerol | PoSSuM |
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Download interaction data: 6GXU
Structure summary
Code : | 6GXU PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of Schistosoma mansoni HDAC8 complexed with an hydroxamate 3 | ||||||||||||
Release Data : | 2018-08-15 | ||||||||||||
Compound : |
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Authors : | Shaik, T.B., Marek, M., Romier, C. | ||||||||||||
Keywords : | Epigenetics, Histone deacetylase, HDAC8, Selective inhibitor, Pathogen, hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.917 Å ) | ||||||||||||
Citation : |
Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.
Bayer, T.,Chakrabarti, A.,Lancelot, J.
et al.
PubMed: 29806110 |
Reaction
Chain : | A, B, C, D | ||||||||||||||||
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UniProt : | A5H660 (A5H660_SCHMA) | ||||||||||||||||
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