PDB ID: 6GUE
Hetero Atom Contents
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Structure summary
Code : | 6GUE PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | CELL CYCLE | ||||||||||||||||||||||||||||||||||||
Title : | CDK2/CyclinA in complex with AZD5438 | ||||||||||||||||||||||||||||||||||||
Release Data : | 2018-12-05 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Wood, D.J., Korolchuk, S., Tatum, N.J., Wang, L.Z., Endicott, J.A., Noble, M.E.M., Martin, M.P. | ||||||||||||||||||||||||||||||||||||
Keywords : | CDK2, CYCLINA, INHIBITOR, CELL CYCLE | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.99 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Wood, D.J.,Korolchuk, S.,Tatum, N.J.
et al.
PubMed: 30472117 |
Reaction
Chain : | C | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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Chain : | B, D |
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UniProt : | P30274 (CCNA2_BOVIN) |
Reaction : | - |