Het-PDB Navi2 (PDB: 6GS4)

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Ligands
Code	Name		Style	Show	Link
F9E	[(2~{S})-2-[(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)methoxy]-3-oxidanyl-propyl] (2~{S})-2-azanyl-3-methyl-butanoate				PoSSuM
LMT	Dodecyl-beta-D-maltoside				PoSSuM

Non-standard Residues
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Download interaction data: 6GS4

Code :

6GS4 PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN

Title :

Crystal structure of peptide transporter DtpA-nanobody in complex with valganciclovir

Release Data :

2019-01-30

Compound :

mol_id	molecule	chains
1	Dipeptide and tripeptide permease A	A

mol_id	molecule	chains
2	nanobody	H

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli K-12 (taxid:83333)	Escherichia coli (taxid:562)
	gene: dtpA, tppB, ydgR, b1634, JW1626 expression_system_variant: C41

mol_id	organism_scientific	expression_system
2	Lama glama (taxid:9844)	Escherichia coli (taxid:562)
	expression_system_variant: WK6

Authors :

Ural-Blimke, Y., Flayhan, A., Quistgaard, E.M., Loew, C.

Keywords :

peptide transporter, membrane protein, complex with nanobody, SLC15 family member

Exp. method :

X-RAY DIFFRACTION ( 2.645 Å )

Citation :

Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.

Ural-Blimke, Y.,Flayhan, A.,Strauss, J. et al.
(2019) J. Am. Chem. Soc. 141 : 2404 - 2412

PDB ID: 6GS4