Het-PDB Navi2 (PDB: 6GR8)

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Ligands
Code	Name		Style	Show	Link
F8Z	1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea				PoSSuM

Non-standard Residues
Code	Name	Show
SEP	Phosphoserine
TPO	Phosphothreonine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 6GR8

Code :

6GR8 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Human AURKC INCENP complex bound to BRD-7880

Release Data :

2019-05-15

Compound :

mol_id	molecule	chains	synonym
1	Aurora kinase C	A	Aurora 3,Aurora/IPL1-related kinase 3,Aurora-related kinase 3,Aurora/IPL1/Eg2 protein 2,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase aurora-C
	ec: 2.7.11.1

mol_id	molecule	chains
2	Inner centromere protein	B

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	gene: AURKC, AIE2, AIK3, AIRK3, ARK3, STK13 expression_system_plasmid: pHTvAmp1-SGC

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: INCENP expression_system_plasmid: pHTvAmp1-SGC

Authors :

Abdul Azeez, K.R., Sorrell, F.J., von Delft, F., Bountra, C., Knapp, S., Edwards, A.M., Arrowsmith, C., Elkins, J.M.

Keywords :

Kinase, Structural Genomics Consortium, SGC, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.75 Å )

Citation :

AURKC INCENP complex bound to BRD-7880

Abdul Azeez, K.R.,Elkins, J.M.
To Be Published

Chain :

UniProt :

Q9UQB9 (AURKC_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]	2.7.11.1	-
	-	-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]	2.7.11.1	-
	-	-

PDB ID: 6GR8