Het-PDB Navi2 (PDB: 6GQW)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
MG	Magnesium ion	PoSSuM
GNP	Phosphoaminophosphonic acid-guanylate ester	PoSSuM
F8T	[4-[[4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 6GQW

Code :

6GQW PDBj RCSB PDB PDBe

Header :

ONCOPROTEIN

Title :

KRAS-169 Q61H GPPNHP + CH-1

Release Data :

2019-02-06

Compound :

mol_id	molecule	chains	synonym
1	GTPase KRas	A,B,C,D,F	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
	mutation: Q61H

mol_id	molecule	chains	synonym
2	GTPase KRas	E	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
	mutation: Q61H

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: KRAS, KRAS2, RASK2

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: KRAS, KRAS2, RASK2

Authors :

Cruz-Migoni, A., Quevedo, C.E., Carr, S.B., Phillips, S.E.V., Rabbitts, T.H.

Keywords :

KRAS, ONCOPROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.8 Å )

Citation :

Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Cruz-Migoni, A.,Canning, P.,Quevedo, C.E. et al.
(2019) Proc. Natl. Acad. Sci. U.S.A. 116 : 2545 - 2550

Chain :

UniProt :

P01116 (RASK_HUMAN)

PDB ID: 6GQW