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Ligands
Code Name Style Show Link
F2Z 6,7-dimethoxy-2,4-dihydro-1~{H}-isoquinolin-3-one
SAH S-adenosyl-L-homocysteine
Non-standard Residues
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Glycosylation
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Code : 6GKY   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of Coclaurine N-Methyltransferase (CNMT) bound to N-methylheliamine and SAH
Release Data : 2018-06-06
Compound :
mol_id molecule chains
1 Coclaurine N-methyltransferase A,B
ec: 2.1.1.115
Source :
mol_id organism_scientific organism_common expression_system
1 Coptis japonica  (taxid:3442) Japanese goldthread Escherichia coli  (taxid:562)
gene: cnmt
Authors : Dunstan, M.S., Levy, C.W.
Keywords : N-methylheliamine, Coclaurine N-Methyltransferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.8470 Å )
Citation :

Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase.

Bennett, M.R.,Thompson, M.L.,Shepherd, S.A.  et al.
(2018)  Angew. Chem. Int. Ed. Engl.  57 : 10600 - 10604

PubMed: 29791083
DOI: 10.1002/anie.201805060

Chain : A, B
UniProt : Q948P7 (Q948P7_COPJA)
Reaction : -