Brand  (β version)

PDB ID: 6FVH

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Ligands
Code Name Style Show Link
0FI N-phenylthioformamide PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 6FVH   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound PITC
Release Data : 2018-06-06
Compound :
mol_id molecule chains synonym
1 Macrophage migration inhibitory factor A,B,C MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
ec: 5.3.2.1,5.3.3.12
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: MIF, GLIF, MMIF
Authors : Samygina, V.R., Bourenkov, G., Sokolov, A.V.
Keywords : ISOMERASE INHIBITOR, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.40 Å )
Citation :

Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor.

Sokolov, A.V.,Dadinova, L.A.,Petoukhov, M.V.  et al.
(2018)  Biochemistry Mosc.  83 : 701 - 707

PubMed: 30195326
DOI: 10.1134/S000629791806007X

Reaction

Chain : A, B, C
UniProt : P14174 (MIF_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
3-phenylpyruvate = enol-phenylpyruvate 5.3.2.1 PubMed:11439086
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L-dopachrome = 5,6-dihydroxyindole-2-carboxylate 5.3.3.12 PubMed:17526494
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