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Ligands
Code Name Style Show Link
ZN Zinc ion
Non-standard Residues
Code Name Show
FOX ((1r,2s,4r)-4-{[2-amino-5-(formylamino)-6-oxo-3,6-dihydropyrimidin-4-yl]amino}-2-hydroxycyclopentyl)methyl 5'-phosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 6FL1   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of the complex between the Lactococcus lactis FPG mutant T221P and a Fapy-dG containing DNA
Release Data : 2019-02-06
Compound :
mol_id molecule chains
1 DNA (5'-D(*CP*TP*CP*TP*TP*TP(FOX)P*TP*TP*TP*CP*TP*CP*G)-3') B
mol_id molecule chains
2 DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3') C
mol_id molecule chains synonym
3 Formamidopyrimidine-DNA glycosylase A Fapy-DNA glycosylase,DNA-(apurinic or apyrimidinic site) lyase MutM,AP lyase MutM
ec: 3.2.2.23,4.2.99.18
mutation: T221P
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific organism_common expression_system
3 Lactococcus lactis subsp. cremoris  (taxid:1359) Streptococcus cremoris Escherichia coli  (taxid:562)
gene: mutM, fpg, NCDO763_0992
Authors : Coste, F., Castaing, B., Ober, M., Carell, T.
Keywords : PROTEIN-DNA COMPLEX, GLYCOSYLASE, FAPY LESION, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.600 Å )
Citation :

Crystal structure of the complex between the Lactococcus lactis FPG mutant T221P and a Fapy-dG containing DNA

Coste, F.,Castaing, B.,Ober, M.  et al.
To Be Published 

Chain : A
UniProt : A0A165FVI1
Reaction : -