Brand  (β version)

PDB ID: 6FDZ

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Ligands
Code Name Style Show Link
C87 Momelotinib PoSSuM
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Glycosylation
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Structure summary

Code : 6FDZ   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Unc-51-Like Kinase 3 (ULK3) In Complex With Momelotinib
Release Data : 2018-08-01
Compound :
mol_id molecule chains synonym
1 Serine/threonine-protein kinase ULK3 U Unc-51-like kinase 3
ec: 2.7.11.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: ULK3
expression_system_common: Fall armyworm
Authors : Mathea, S., Salah, E., Moroglu, M., Scorah, A., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Huber, K., Knapp, S.
Keywords : Kinase Inhibitor DFG-out, transferase
Exp. method : X-RAY DIFFRACTION ( 2.55 Å )
Citation :

Unc-51-Like Kinase 3 (ULK3) In Complex With Momelotinib

Mathea, S.,Salah, E.,Moroglu, M.  et al.
To Be Published 

Reaction

Chain : U
UniProt : Q6PHR2 (ULK3_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 -
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 -
-