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Ligands
Code Name Style Show Link
CA Calcium ion
CWH [(2~{S},5~{R},8~{S},11~{S})-1-[(2~{R},3~{R},5~{R},6~{S})-3,5-dimethyl-6-oxidanyl-4-oxidanylidene-oxan-2-yl]-5,11-dimethyl-8-oxidanyl-13-[[(2~{S})-2-oxidanylpropanoyl]amino]tridecan-2-yl] ethanoate
FAD Flavin-adenine dinucleotide
GOL Glycerol
Non-standard Residues
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Code : 6F7V   PDBj   RCSB PDB   PDBe
Header : FLAVOPROTEIN
Title : Crystal structure of LkcE E64Q mutant in complex with LC-KA05
Release Data : 2018-09-19
Compound :
mol_id molecule chains synonym
1 LkcE A,B Amine oxidase
ec: 1.4.3.4
mutation: E64Q
Source :
mol_id organism_scientific expression_system
1 Streptomyces rochei subsp. volubilis  (taxid:885435) Escherichia coli BL21(DE3)  (taxid:469008)
gene: lkcE
Authors : Dorival, J., Risser, F., Jacob, C., Collin, S., Drager, G., Kirschning, A., Paris, C., Chagot, B., Gruez, A., Weissman, K.J.
Keywords : Amine oxydase, cyclase, Post-PKS enzyme, tayloring enzyme, FLAVOPROTEIN
Exp. method : X-RAY DIFFRACTION ( 3.0300 Å )
Citation :

Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.

Dorival, J.,Risser, F.,Jacob, C.  et al.
(2018)  Nat Commun  9 : 3998 - 3998

PubMed: 30266997
DOI: 10.1038/s41467-018-06323-w

Chain : A, B
UniProt : G4V2H3 (G4V2H3_STRRO)
Reaction : -