Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
ACP Phosphomethylphosphonic acid adenylate ester
CA Calcium ion
CVT 3,4,5-trimethoxy-~{N}-[(~{E})-naphthalen-1-ylmethylideneamino]benzamide
GDP Guanosine-5'-diphosphate
GTP Guanosine-5'-triphosphate
MES 2-(N-morpholino)-ethanesulfonic acid
MG Magnesium ion
Code : 6F7C
Header : CELL CYCLE
Title : TUBULIN-Compound 12 complex
Release Data : 2018-12-19
Compound :
mol_id molecule chains synonym
1 Tubulin alpha-1B chain A,C Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
mol_id molecule chains
2 Tubulin beta-2B chain B,D
mol_id molecule chains synonym
3 Stathmin-4 E Stathmin-like protein B3,RB3
mol_id molecule chains
4 Tubulin tyrosine ligase F
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Bovine
organ: Brain
mol_id organism_scientific organism_common
2 Bos taurus  (taxid:9913) Bovine
organ: Brain
mol_id organism_scientific organism_common expression_system
3 Rattus norvegicus  (taxid:10116) Rat Escherichia coli  (taxid:562)
gene: Stmn4
mol_id organism_scientific organism_common expression_system
4 Gallus gallus  (taxid:9031) Chicken Escherichia coli  (taxid:562)
gene: TTL
Authors : Muehlethaler, T., Prota, A.E., Steinmetz, M.O.
Keywords : CELL CYCLE, TUBULIN FOLD, CYTOSKELETON, MICROTUBULE
Exp. method : X-RAY DIFFRACTION ( 2.002 Å )
Citation :

Structural Basis of Colchicine-Site targeting Acylhydrazones active against Multidrug-Resistant Acute Lymphoblastic Leukemia.

Cury, N.M.,Muhlethaler, T.,Laranjeira, A.B.A.  et al.
(2019)  Iscience  21 : 95 - 109

PubMed: 31655259
DOI: 10.1016/j.isci.2019.10.003

Chain : A, C
UniProt : P81947 (TBA1B_BOVIN)
Reaction : -
Chain : B, D
UniProt : Q6B856 (TBB2B_BOVIN)
Reaction : -
Chain : E
UniProt : P63043 (STMN4_RAT)
Reaction : -
Chain : F
UniProt : E1BQ43 (No found in current UniProtKB/SwissProt)
Reaction : -