PDB ID: 6EZ9
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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C68 | (2~{S})-2-[[(2~{S})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]oxycarbonylamino]pentanedioic acid | PoSSuM | |||
CA | Calcium ion | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
Code | Name | Show |
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Code | Name | Emphasize |
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BMA | Beta-D-mannopyranose | |
MAN | Alpha-D-mannopyranose | |
NAG | 2-acetamido-2-deoxy-beta-D-glucopyranose |
Code | Name | Show |
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Download interaction data: 6EZ9
Structure summary
Code : | 6EZ9 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive mutant, in complex with a inhibitor JHU3372 | ||||||||||||
Release Data : | 2018-12-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Barinka, C., Novakova, Z., Motlova, L. | ||||||||||||
Keywords : | glutamate carboxypeptidase II (GCPII); NAALADase; prostate-specific membrane antigen; phosphoramidate, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.61 Å ) | ||||||||||||
Citation : |
Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Barinka, C.,Novakova, Z.,Hin, N.
et al.
PubMed: 30552009 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q04609 (FOLH1_HUMAN) | ||||||||
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