PDB ID: 6EXL
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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C2Q | [(3~{R})-3-carboxy-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium | PoSSuM | |||
IPA | Isopropyl alcohol | PoSSuM | |||
NA | Sodium ion | PoSSuM |
Code | Name | Show |
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CME | S,S-(2-hydroxyethyl)thiocysteine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 6EXL
Structure summary
Code : | 6EXL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | DNA BINDING PROTEIN | ||||||||||||
Title : | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - folded HTH motif | ||||||||||||
Release Data : | 2018-05-02 | ||||||||||||
Compound : |
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Source : |
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Authors : | Hall, M., Grundstrom, C., Begum, A., Kulen, M., Lindgren, M., Johansson, J., Almqvist, F., Sauer, U.H., Sauer-Eriksson, A.E. | ||||||||||||
Keywords : | Transcription regulator, DNA binding, 2-pyridone, drug design, Listeria monocytogenes, DNA BINDING PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||
Citation : |
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
Kulen, M.,Lindgren, M.,Hansen, S.
et al.
PubMed: 29667825 Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
Good, J.A.,Andersson, C.,Hansen, S.
et al.
PubMed: 26991105 |
Reaction
Chain : | A, B |
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UniProt : | Q4TVQ0 (Q4TVQ0_LISMN) |
Reaction : | - |