PDB ID: 6EX8
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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C2K | (3~{S})-~{N}-[1-(aminomethyl)cyclopropyl]-19-chloranyl-5-oxidanylidene-9-(trifluoromethyl)-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM |
Code | Name | Show |
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CSX | S-oxy cysteine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 6EX8
Structure summary
Code : | 6EX8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | ||||||||||||
Release Data : | 2018-04-11 | ||||||||||||
Compound : |
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Source : |
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Authors : | Dietzel, U., Kisker, C. | ||||||||||||
Keywords : | Cysteine Protease, Papain-like Protease, Cathepsin L-like Protease, Endopeptidase, Hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.6000 Å ) | ||||||||||||
Citation : |
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
Giroud, M.,Dietzel, U.,Anselm, L.
et al.
PubMed: 29590750 |
Reaction
Chain : | A, B |
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UniProt : | Q95PM0 (Q95PM0_TRYBR) |
Reaction : | - |