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Ligands
Code Name Style Show Link
0O2 Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
FE2 Fe (II) ion
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Code : 6EX0   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to pppGpp in the post-catalytic state
Release Data : 2018-01-24
Compound :
mol_id molecule chains synonym
1 GTP pyrophosphokinase A,B GTP pyrophosphokinase ywaC,RelA/SpoT domain protein
ec: 2.7.6.5
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus  (taxid:1280) Escherichia coli BL21(DE3)  (taxid:469008)
gene: ywaC, AB454_12730, AB466_12625, AB478_12605, AB526_12980, AFO97_10970, AFP37_10975, EP54_00695, EQ90_03295, ERS072738_01254, ERS074020_00750, HMPREF3211_00175
Authors : Manav, M.C., Brodersen, D.E.
Keywords : stringent response, (p)ppGpp, persistence, small alarmone synthetase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.78 Å )
Citation :

Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.

Manav, M.C.,Beljantseva, J.,Bojer, M.S.  et al.
(2018)  J. Biol. Chem.  293 : 3254 - 3264

PubMed: 29326162
DOI: 10.1074/jbc.RA117.001374

Chain : A, B
UniProt : W8U368 (W8U368_STAAU)
Reaction : -