Het-PDB Navi2 (PDB: 6EW6)

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Ligands
Code	Name		Style	Show	Link
C0H	~{N}2-(2-chlorophenyl)-1,3,5-triazine-2,4-diamine				PoSSuM

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Download interaction data: 6EW6

Code :

6EW6 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand

Release Data :

2018-10-24

Compound :

mol_id	molecule	chains	synonym
1	B-cell lymphoma 6 protein	A	BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli-Pichia pastoris shuttle vector pPpARG4 (taxid:1182032)
	gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51

Authors :

Robb, G., Ferguson, A., Hargreaves, D.

Keywords :

KINASE, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.39 Å )

Citation :

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.

McCoull, W.,Cheung, T.,Anderson, E. et al.
(2018) ACS Chem. Biol. 13 : 3131 - 3141

PDB ID: 6EW6