PDB ID: 6EV0
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
BYK | [(3~{R})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium | PoSSuM | |||
C8N | [(3~{S})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium | PoSSuM | |||
IPA | Isopropyl alcohol | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 6EV0
Structure summary
Code : | 6EV0 PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | DNA BINDING PROTEIN | ||||||||||||
Title : | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (AC129) | ||||||||||||
Release Data : | 2018-05-02 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Begum, A., Hall, M., Grundstrom, C., Cairns, A.G., Kulen, M., Lindgren, M., Johansson, J., Almqvist, F., Sauer, U.H., Sauer-Eriksson, A.E. | ||||||||||||
Keywords : | Transcription regulator, DNA binding, 2-pyridone, drug design, Listeria monocytogenes, DNA BINDING PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.30 Å ) | ||||||||||||
Citation : |
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
Kulen, M.,Lindgren, M.,Hansen, S.
et al.
PubMed: 29667825 Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
Good, J.A.,Andersson, C.,Hansen, S.
et al.
PubMed: 26991105 |
Reaction
Chain : | A, B |
---|---|
UniProt : | P22262 (PRFA_LISMO) |
Reaction : | - |