PDB ID: 6EGD
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Structure summary
Code : | 6EGD PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor | ||||||||||||
Release Data : | 2019-02-13 | ||||||||||||
Compound : |
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Source : |
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Authors : | Ferrao, R., Wu, H. | ||||||||||||
Keywords : | Kinase, Unphosphorylated, Inactive, SIGNALING PROTEIN, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.100 Å ) | ||||||||||||
Citation : |
Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
Wang, L.,Ferrao, R.,Li, Q.
et al.
PubMed: 30679311 |
Reaction
Chain : | D, A | ||||||||||||
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UniProt : | Q9NWZ3 (IRAK4_HUMAN) | ||||||||||||
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