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Ligands
Code Name Style Show Link
J4G 3'-deoxy-3'-[(L-alpha-glutamyl)amino]adenosine 5'-(dihydrogen phosphate)
Non-standard Residues
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Glycosylation
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Code : 6EC8   PDBj   RCSB PDB   PDBe
Header : BIOSYNTHETIC PROTEIN
Title : Glutamylation domain, TbtB, from thiomuracin biosynthesis bound to 5'-phosphodesmethylglutamycin
Release Data : 2019-06-19
Compound :
mol_id molecule chains
1 Lantibiotic dehydratase domain protein A
Source :
mol_id organism_scientific expression_system
1 Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)  (taxid:469371) Escherichia coli BL21(DE3)  (taxid:469008)
strain: ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51
variant: ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51
atcc: 19993
gene: Tbis_0550
expression_system_plasmid: pET28
Authors : Cogan, D.P., Nair, S.K.
Keywords : RiPP, thiopeptide, thiomuracin, tRNA-dependent, glutamylation, dehydratase, BIOSYNTHETIC PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.148 Å )
Citation :

Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.

Bothwell, I.R.,Cogan, D.P.,Kim, T.  et al.
(2019)  Proc.Natl.Acad.Sci.USA  116 : 17245 - 17250

PubMed: 31409709
DOI: 10.1073/pnas.1905240116

Chain : A
UniProt : D6Y502 (D6Y502_THEBD)
Reaction : -