PDB ID: 6EA9
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Structure summary
Code : | 6EA9 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Structure of VACV Poxin in post-reactive state with Gp[2'-5']Ap[3'] | ||||||||||||
Release Data : | 2019-02-06 | ||||||||||||
Compound : |
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Source : |
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Authors : | Eaglesham, J.B., Kranzusch, P.J. | ||||||||||||
Keywords : | Vaccina virus, nuclease, cGAS, cGAMP, poxvirus, innate immunity, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.100 Å ) | ||||||||||||
Citation : |
Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.
Eaglesham, J.B.,Pan, Y.,Kupper, T.S.
et al.
PubMed: 30728498 |
Reaction
Chain : | A, B, C, D, E | |||||||||
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UniProt : | Q01225 (POXIN_VACCW) | |||||||||
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