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Ligands
Code Name Style Show Link
MPD (4s)-2-methyl-2,4-pentanediol
Non-standard Residues
Code Name Show
CHG Cyclohexyl-glycine
MEA N-methylphenylalanine
ORN L-ornithine
Glycosylation
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Modification
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Code : 6DR5   PDBj   RCSB PDB   PDBe
Header : DE NOVO PROTEIN
Title : X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36 containing the I31Chg point mutation
Release Data : 2018-10-17
Compound :
mol_id molecule chains
1 ORT-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORT-ALA-CHG-ILE-GLY-LEU-ORA-VAL A,B,C,D,E,F
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
synthetic: yes
Authors : Salveson, P.J., Nowick, J.S.
Keywords : Amyloid, Alzheimers Disease, Abeta, oligomer, DE NOVO PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.079 Å )
Citation :

Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from A beta.

Salveson, P.J.,Haerianardakani, S.,Thuy-Boun, A.  et al.
(2018)  J. Am. Chem. Soc.  140 : 11745 - 11754

PubMed: 30125493
DOI: 10.1021/jacs.8b06568