PDB ID: 6DKB
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FKY | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | PoSSuM |
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Download interaction data: 6DKB
Structure summary
Code : | 6DKB PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10b. | ||||||||||||
Release Data : | 2018-07-11 | ||||||||||||
Compound : |
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Authors : | Greasley, S.E., Johnson, E., Kraus, M.L., Cronin, C.N. | ||||||||||||
Keywords : | Inhibitor Tyrosine kinase, TRANSFERASE, pan-Trk Kinase, Treatment for pain, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.68 Å ) | ||||||||||||
Citation : |
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.
Bagal, S.K.,Andrews, M.,Bechle, B.M.
et al.
PubMed: 29944371 |
Reaction
Chain : | A | ||||||||
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UniProt : | P04629 (NTRK1_HUMAN) | ||||||||
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