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Ligands
Code Name Style Show Link
9DG 9-deazaguanine
ACT Acetate ion
EDO 1,2-ethanediol
MG Magnesium ion
PEG Di(hydroxyethyl)ether
PRP 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose
Non-standard Residues
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Glycosylation
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Code : 6D9R   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase)
Release Data : 2019-05-01
Compound :
mol_id molecule chains synonym
1 Hypoxanthine phosphoribosyltransferase A,B HPRT
ec: 2.4.2.8
Source :
mol_id organism_scientific expression_system
1 Bacillus anthracis  (taxid:1392) Escherichia coli BL21(DE3)  (taxid:469008)
gene: hpt, hprT, hpt1, tilS, BA_0063, A9486_05730, ABW01_27435, BASH2_00187, BVG01_28865, CN272_24955, CN488_12230, CN504_22375, COE56_22980, COJ30_24475, COK92_19380, COL95_25280, MCCC1A01412_27610
expression_system_vector_type: plasmid
expression_system_plasmid: pLIC trPC-HA
Authors : Satyshur, K.A., Wolak, C., Anderson, B., Dubiel, K., Keck, J.L.
Keywords : HPRT, hypoxanthine phosphoribosyltransferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.640 Å )
Citation :

Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.

Anderson, B.W.,Liu, K.,Wolak, C.  et al.
(2019)  Elife  8

PubMed: 31552824
DOI: 10.7554/eLife.47534

Chain : A, B
UniProt : A0A1S0QLD4
Reaction : -