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Ligands
Code Name Style Show Link
CA Calcium ion
DTB 6-(5-methyl-2-oxo-imidazolidin-4-yl)-hexanoic acid
FZ4 2-aminoethyl diphenylborinate
Non-standard Residues
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Code : 6D7Q   PDBj   RCSB PDB   PDBe
Header : membrane protein/inhibitor
Title : Crystal Structure of Rat TRPV6*-Y466A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Release Data : 2018-07-18
Compound :
mol_id molecule chains synonym
1 Transient receptor potential cation channel subfamily V member 6 A TrpV6,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Rat Homo sapiens  (taxid:9606)
gene: Trpv6
Authors : Singh, A.K., Saotome, K., McGoldrick, L.L., Sobolevsky, A.I.
Keywords : Ion channels, transporter, calcium channel, epithelial calcium channel, MEMBRANE PROTEIN, membrane protein-inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 3.497 Å )
Citation :

Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.

Singh, A.K.,Saotome, K.,McGoldrick, L.L.  et al.
(2018)  Nat Commun  9 : 2465 - 2465

PubMed: 29941865
DOI: 10.1038/s41467-018-04828-y

Chain : A
UniProt : Q9R186 (TRPV6_RAT)
Reaction : -