Het-PDB Navi2 (PDB: 6D3E)

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Ligands

Code	Name		Style	Show	Link
FT7	1-[(2,4-difluorophenyl)methyl]-2,3-dimethyl-N-[(1r)-1-phenylpropyl]-1h-indole-5-carboxamide				PoSSuM

Interaction

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Download interaction data: 6D3E

Code :

6D3E PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

PPARg LBD in Complex with SR1988

Release Data :

2019-02-27

Compound :

mol_id	molecule	chains	synonym
1	Peroxisome proliferator-activated receptor gamma	A,B	PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
	fragment: Ligand Binding Domain

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: PPARG, NR1C3 expression_system_strain: BL21(DE3)

Authors :

Frkic, R.L., Bruning, J.B.

Keywords :

type 2 diabetes, nuclear receptor, drug discovery, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.3950 Å )

Citation :

Structural and Dynamic Elucidation of a Non-acid PPARgammaPartial Agonist: SR1988.

Frkic, R.L.,Chua, B.S.,Shin, Y. et al.
(2018) Nucl Receptor Res 5

PDB ID: 6D3E