Het-PDB Navi2 (PDB: 6D32)

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Ligands
Code	Name		Style	Show	Link
CY8	Cyclopamine				PoSSuM

Non-standard Residues
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Download interaction data: 6D32

Code :

6D32 PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN

Title :

Crystal structure of Xenopus Smoothened in complex with cyclopamine

Release Data :

2018-05-23

Compound :

mol_id	molecule	chains	synonym
1	Smoothened,Soluble cytochrome b562,Smoothened	A	Cytochrome b-562

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Xenopus laevis (taxid:8355)	African clawed frog	Spodoptera frugiperda (taxid:7108)
	gene: smo, Smo

Authors :

Huang, P., Zheng, S., Kim, Y., Kruse, A.C., Salic, A.

Keywords :

GPCR, Hedgehog signaling, Class Frizzled, Sterol, MEMBRANE PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 3.7510 Å )

Citation :

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Huang, P.,Zheng, S.,Wierbowski, B.M. et al.
(2018) Cell 174 : 312 - 324.e16

PDB ID: 6D32