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Ligands
Code Name Style Show Link
GOL Glycerol
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
: Polysaccharide
Non-standard Residues
Code Name Show
BUC S,S-butylthiocysteine
FOD (2s)-2-amino-4-[1-(trans-4-hydroxycyclohexyl)-1h-1,2,3-triazol-4-yl]butanoic acid
Glycosylation
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Code Name Show
Code : 6CXG   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : anti-HIV-1 Fab 2G12 in complex with glycopeptide 10V1S
Release Data : 2019-02-20
Compound :
mol_id molecule chains
1 anti-HIV-1 Fab 2G12 light chain L,K
mol_id molecule chains
2 anti-HIV-1 Fab 2g12 heavy chain H,M
mol_id molecule chains
3 10V1S glycopeptide A,C
Source :
mol_id organism_scientific expression_system
1 Homo sapiens  (taxid:9606) Homo sapiens  (taxid:9606)
expression_system_cell_line: 293freestyle
mol_id organism_scientific expression_system
2 Homo sapiens  (taxid:9606) Homo sapiens  (taxid:9606)
expression_system_cell_line: 293freestyle
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Stanfield, R.L., Wilson, I.A.
Keywords : antibody, glycopeptide, HIV-1, glycobiology, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.298 Å )
Citation :

Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.

Nguyen, D.N.,Xu, B.,Stanfield, R.L.  et al.
(2019)  ACS Cent Sci  5 : 237 - 249

PubMed: 30834312
DOI: 10.1021/acscentsci.8b00588