Het-PDB Navi2 (PDB: 6CVH)

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Ligands
Code	Name		Style	Show	Link
FJG	Trans-3-({4-(cyclohexylmethyl)-5-[3-(1-methylcyclopropyl)-5-{[(2r)-1,1,1-trifluoropropan-2-yl]carbamoyl}phenyl]-1,3-thiazole-2-carbonyl}amino)cyclobutane-1-carboxylic acid				PoSSuM

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Download interaction data: 6CVH

Code :

6CVH PDBj RCSB PDB PDBe

Header :

NUCLEAR PROTEIN

Title :

Identification and biological evaluation of thiazole-based inverse agonists of RORgt

Release Data :

2018-04-25

Compound :

mol_id	molecule	chains	synonym
1	Nuclear receptor ROR-gamma	A	Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: RORC, NR1F3, RORG, RZRG

Authors :

Spurlino, J., Milligan, C.

Keywords :

Nuclear Receptor RORgt, NUCLEAR PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 3.5000 Å )

Citation :

Identification and biological evaluation of thiazole-based inverse agonists of ROR gamma t.

Gege, C.,Cummings, M.D.,Albers, M. et al.
(2018) Bioorg. Med. Chem. Lett. 28 : 1446 - 1455

PDB ID: 6CVH