Brand  (β version)

PDB ID: 6CTS

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Ligands
Code Name Style Show Link
CIC Citryl-thioether-coenzyme *a PoSSuM
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Structure summary

Code : 6CTS   PDBj   RCSB PDB   PDBe
Header : OXO-ACID-LYASE
Title : PROPOSED MECHANISM FOR THE CONDENSATION REACTION OF CITRATE SYNTHASE. 1.9-ANGSTROMS STRUCTURE OF THE TERNARY COMPLEX WITH OXALOACETATE AND CARBOXYMETHYL COENZYME A
Release Data : 1990-10-15
Compound :
mol_id molecule chains
1 CITRATE SYNTHASE A
ec: 4.1.3.7
Source :
mol_id organism_scientific organism_common
1 Gallus gallus  (taxid:9031) Chicken
Authors : Karpusas, M., Branchaud, B., Remington, S.J.
Keywords : OXO-ACID-LYASE
Exp. method : X-RAY DIFFRACTION ( 2.5 Å )
Citation :

Proposed mechanism for the condensation reaction of citrate synthase: 1.9-A structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A.

Karpusas, M.,Branchaud, B.,Remington, S.J.
(1990)  Biochemistry  29 : 2213 - 2219

PubMed: 2337600
DOI: 10.1021/bi00461a002

Crystal Structure Analysis and Molecular Model of a Complex of Citrate Synthase with Oxaloacetate and S-Acetonyl-Coenzymea

Wiegand, G.,Remington, S.,Deisenhofer, J.  et al.
(1984)  J.Mol.Biol.  174 : 205

Crystallographic Refinement and Atomic Models of Two Different Forms of Citrate Synthase at 2.7 And 1.7 Angstroms Resolution

Remington, S.,Wiegand, G.,Huber, R.
(1982)  J.Mol.Biol.  158 : 111

Primary Structure of Porcine Heart Citrate Synthase

Bloxham, D.P.,Parmelee, D.C.,Kumar, S.  et al.
(1981)  Proc.Natl.Acad.Sci.USA  78 : 5381

Crystal Structure Analysis of the Tetragonal Crystal Form and Preliminary Molecular Model of Pig-Heart Citrate Synthase

Wiegand, G.,Kukla, D.,Scholze, H.  et al.
(1979)  Eur.J.Biochem.  93 : 41

Reaction

Chain : A
UniProt : P23007 (CISY_CHICK)
Reaction: EC: Evidence:
Physiological Direction:
acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+) 2.3.3.1 PROSITE- ProRule:PRU10117, PubMed:2337600
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