Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CIT Citric acid
COF Trifluoroacetonyl coenzyme a
Code : 6CSC
Header : OXO-ACID-LYASE
Title : CHICKEN CITRATE SYNTHASE COMPLEX WITH TRIFLUOROACETONYL-COA AND CITRATE
Release Data : 1997-12-24
Compound :
mol_id molecule chains
1 CITRATE SYNTHASE A,B
ec: 4.1.3.7
Source :
mol_id organism_scientific organism_common
1 Gallus gallus  (taxid:9031) Chicken
organ: HEART
tissue: MUSCLE
organelle: MITOCHONDRIA
cellular_location: INNER MATRIX
Authors : Usher, K.C., Remington, S.J.
Keywords : OXO-ACID-LYASE, TRICARBOXYLIC ACID CYCLE, ALLOSTERIC ENZYME
Exp. method : X-RAY DIFFRACTION ( 2.25 Å )
Citation :

Trifluoroacetonyl Coenzyme A, an Inhibitor of Citrate Synthase, Binds in a Combination of Productive and Nonproductive Modes

Usher, K.C.,Branchaud, B.,Remington, S.J.
To be Published 

A Very Short Hydrogen Bond Provides Only Moderate Stabilization of an Enzyme-Inhibitor Complex of Citrate Synthase

Usher, K.C.,Remington, S.J.,Martin, D.P.  et al.
(1994)  Biochemistry  33 : 7753

Crystal Structure Analysis and Molecular Model of a Complex of Citrate Synthase with Oxaloacetate and S-Acetonyl-Coenzyme A

Wiegand, G.,Remington, S.,Deisenhofer, J.  et al.
(1984)  J.Mol.Biol.  174 : 205

Crystallographic Refinement and Atomic Models of Two Different Forms of Citrate Synthase at 2.7 And 1.7 A Resolution

Remington, S.,Wiegand, G.,Huber, R.
(1982)  J.Mol.Biol.  158 : 111

Chain : A, B
UniProt : P23007 (CISY_CHICK)
Reaction : Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.