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Ligands
Code Name Style Show Link
F9Y 1h-indole-6-carbonitrile
NA Sodium ion
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Glycosylation
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Code : 6CS8   PDBj   RCSB PDB   PDBe
Header : PROTEIN TRANSPORT
Title : High resolution crystal structure of FtsY-NG domain of E. coli
Release Data : 2018-08-22
Compound :
mol_id molecule chains synonym
1 Signal recognition particle receptor FtsY A,B SRP receptor
Source :
mol_id organism_scientific expression_system
1 Escherichia coli (strain K12)  (taxid:83333) Escherichia coli 'BL21-Gold(DE3)pLysS AG'  (taxid:866768)
strain: K12
gene: ftsY, b3464, JW3429
Authors : Faoro, C., Ataide, S.F.
Keywords : cotranslational delivery SRP, PROTEIN TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 1.749 Å )
Citation :

Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.

Faoro, C.,Wilkinson-White, L.,Kwan, A.H.  et al.
(2018)  PLoS ONE  13 : e0200387 - e0200387

PubMed: 30044812
DOI: 10.1371/journal.pone.0200387

Chain : A, B
UniProt : P10121 (FTSY_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
GTP + H2O = GDP + H(+) + phosphate 3.6.5.4 HAMAP-Rule:MF_00920, PubMed:11735405, PubMed:17682051
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