PDB ID: 6CQ5
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Structure summary
Code : | 6CQ5 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | TBK1 in Complex with Sulfone Analog of Amlexanox | ||||||||||||
Release Data : | 2018-12-05 | ||||||||||||
Compound : |
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Source : |
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Authors : | Beyett, T.S., Tesmer, J.J.G. | ||||||||||||
Keywords : | TBK1, kinase, amlexanox, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.3540 Å ) | ||||||||||||
Citation : |
Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK epsilon for the treatment of obesity.
Beyett, T.S.,Gan, X.,Reilly, S.M.
et al.
PubMed: 30270002 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q9UHD2 (TBK1_HUMAN) | ||||||||||||
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