Brand  (β version)

color scheme of protein:


interaction residue:

chain: Hide other chain(s)

Code Name Link
BR Bromide ion
GOL Glycerol
SO4 Sulfate ion
Modified Residues
Code Name Link
DAL D-alanine
DAR D-arginine
DAS D-aspartic acid
DCY D-cysteine
DGL D-glutamic acid
DGN D-glutamine
DIL D-isoleucine
DLE D-leucine
DLY D-lysine
DSN D-serine
DTH D-threonine
DTR D-tryptophan
F9D (2r)-2-aminopent-4-ynoic acid
LPH L-propargylglycine
MED D-methionine
MSE Selenomethionine
NH2 Amino group
Code : 6CNU
Header : TOXIN
Title : Crystal Structure of JzTX-V
Release Data : 2019-03-06
Compound :
mol_id molecule chains
1 JzTx-V(D) A
mol_id molecule chains
2 JzTx-V B
Source :
mol_id organism_scientific organism_common
1 Chilobrachys guangxiensis  (taxid:278060) Chinese earth tiger tarantula
synthetic: yes
mol_id organism_scientific organism_common
2 Chilobrachys guangxiensis  (taxid:278060) Chinese earth tiger tarantula
synthetic: yes
Authors : Min, X., Wang, Z.
Keywords : inhibitor cysteine knot, TOXIN
Exp. method : X-RAY DIFFRACTION ( 1.0500 Å )
Citation :

Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis.

Wu, B.,Murray, J.K.,Andrews, K.L.  et al.
(2018)  J. Med. Chem.  61 : 9500 - 9512

PubMed: 30346167
DOI: 10.1021/acs.jmedchem.8b00736

Chain : B
UniProt : Q2PAY4 (JZTX5_CHIGU)
Reaction : -