PDB ID: 6CHN
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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F1D | Methyl 4-(3-{(1r)-2-cyano-1-[(5-methyl-7-oxo-6,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)amino]ethyl}phenoxy)piperidine-1-carboxylate | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
PEG | Di(hydroxyethyl)ether | PoSSuM | |||
PG4 | Tetraethylene glycol | PoSSuM |
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Download interaction data: 6CHN
Structure summary
Code : | 6CHN PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/ANTIBIOTIC | ||||||||||||
Title : | Phosphopantetheine adenylyltransferase (CoaD) in complex with methyl (R)-4-(3-(2-cyano-1-((5-methyl-7-oxo-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)amino)ethyl)phenoxy)piperidine-1-carboxylate | ||||||||||||
Release Data : | 2018-04-04 | ||||||||||||
Compound : |
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Source : |
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Authors : | Mamo, M., Appleton, B.A. | ||||||||||||
Keywords : | Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT CaaD, FBDD Gram-negative antibacterial antibiotic, Transferase Transferase-antibiotic complex, TRANSFERASE-ANTIBIOTIC complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.0300 Å ) | ||||||||||||
Citation : |
Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
Skepper, C.K.,Moreau, R.J.,Appleton, B.A.
et al.
PubMed: 29551072 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P0A6I6 (COAD_ECOLI) | ||||||||
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