PDB ID: 6BYZ
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
J18 | [(8r,9s,10s)-9-(2',3'-dimethyl[1,1'-biphenyl]-4-yl)-6-{[2-(trifluoromethyl)phenyl]sulfonyl}-1,6-diazabicyclo[6.2.0]decan-10-yl]methanol | PoSSuM | |||
EPE | 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 6BYZ
Structure summary
Code : | 6BYZ PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE/INHIBITOR | ||||||||||||||||||||||||
Title : | Structure of Cysteine-free Human Insulin-Degrading Enzyme in complex with Substrate-selective Macrocyclic Inhibitor 37 | ||||||||||||||||||||||||
Release Data : | 2019-04-03 | ||||||||||||||||||||||||
Compound : |
|
||||||||||||||||||||||||
Source : |
|
||||||||||||||||||||||||
Authors : | Tan, G.A., Seeliger, M.A., Maianti, J.P., Liu, D.R. | ||||||||||||||||||||||||
Keywords : | Insulin, Glucagon, Diabetes, Exo-site, HYDROLASE, HYDROLASE-INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.95624845742 Å ) | ||||||||||||||||||||||||
Citation : |
Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme.
Maianti, J.P.,Tan, G.A.,Vetere, A.
et al.
PubMed: 31086331 |
Reaction
Chain : | A, B | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P14735 (IDE_HUMAN) | ||||||||
|