Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
CYS Cysteine
FE2 Fe (II) ion
GOL Glycerol
SO4 Sulfate ion
Modified Residues
Code Name Link
F2Y 3,5-difluoro-L-tyrosine
Code : 6BPS
Header : OXIDOREDUCTASE
Title : Crystal structure of cysteine-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase
Release Data : 2018-07-04
Compound :
mol_id molecule chains synonym
1 Cysteine dioxygenase type 1 A Cysteine dioxygenase type I, CDO-I
ec: 1.13.11.20
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: CDO1
Authors : Liu, A., Li, J., Shin, I.
Keywords : Cysteine, Cys-Tyr cofactor, iron, unnatural amino acid, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.

Li, J.,Griffith, W.P.,Davis, I.  et al.
(2018)  Nat. Chem. Biol.  14 : 853 - 860

PubMed: 29942080
DOI: 10.1038/s41589-018-0085-5

Chain : A
UniProt : Q16878 (CDO1_HUMAN)
Reaction : L-cysteine + O(2) = 3-sulfinoalanine.